Pregabalin 75 mg Capsules – Medicine Information & Safety

Pregabalin 75 mg is an oral prescription medicine containing the active substance pregabalin. It belongs to the pharmacotherapeutic group of medicines used in neurological conditions.

In the European Union, authorized pregabalin medicines are indicated for adults with neuropathic pain, as adjunctive treatment for partial seizures, and for generalized anxiety disorder (GAD). Pregabalin capsules are prescription-only medicines.

What Is Pregabalin?

Pregabalin is a medicine that affects signaling within the central nervous system. Although it is structurally related to the neurotransmitter GABA, its biological activity is different. EMA information explains that pregabalin is thought to affect calcium entry into nerve cells, reducing the release of certain neurotransmitters involved in pain and other neurological processes.

Medical Uses

Authorized European pregabalin medicines may be prescribed for the following conditions in adults:

Neuropathic Pain

Pregabalin is indicated for peripheral and central neuropathic pain, meaning pain associated with damage or dysfunction of nerves. Examples described by the EMA include peripheral neuropathic pain associated with diabetes or shingles and central neuropathic pain following spinal-cord injury.

Epilepsy

Pregabalin is indicated as adjunctive therapy for adults with partial seizures, including partial seizures with or without secondary generalization. It is used alongside other epilepsy treatment where appropriate.

Generalized Anxiety Disorder

In the EU, pregabalin is also authorized for the treatment of generalized anxiety disorder (GAD) in adults.

How Pregabalin Works

Pregabalin is not simply a replacement for GABA. According to the EMA, it is thought to influence calcium entry into nerve cells, which can reduce the release of certain neurotransmitters involved in neurological signaling. The precise mechanism underlying all of its clinical effects is not completely understood.

Pregabalin 75 mg Capsules

Pregabalin is available in capsule formulations in several strengths, including 75 mg. The exact formulation, manufacturer, appearance and authorized indications can differ between products and countries.

The 75 mg strength should not be interpreted as an individualized treatment recommendation. Appropriate treatment decisions depend on the authorized product information and a healthcare professional’s assessment.

Side Effects and Safety

Like other prescription medicines, pregabalin can cause adverse effects.

Reported effects can include:

• Dizziness
• Sleepiness or drowsiness
• Blurred or impaired vision
• Dry mouth
• Peripheral swelling
• Weight gain
• Other neurological or gastrointestinal effects

The likelihood and severity of adverse effects can vary between individuals.

Patients should consult a healthcare professional or pharmacist for advice concerning persistent, severe or unexpected symptoms.

Important Precautions

Pregabalin can affect alertness and coordination. Patients should understand how the medicine affects them before undertaking activities requiring full attention.

Healthcare professionals should be informed about other medicines and substances being used because interactions and additive effects may be clinically important.

Pregabalin treatment should be managed according to the authorized product information. Treatment should not be started, stopped or changed without appropriate medical advice.

Dependence and Withdrawal Considerations

Pregabalin treatment requires appropriate medical supervision. Stopping treatment may need to be managed gradually rather than abruptly, depending on the clinical circumstances and prescribing information.

Patients should follow their prescriber’s instructions and seek professional advice before making changes to treatment.

Prescription and Regulatory Status

Pregabalin is a prescription medicine in the European Union. The EMA identifies authorized pregabalin medicines as prescription-only products.

Different pregabalin products and marketing authorizations exist across Europe, and the regulatory status of an individual product can change. Patients and healthcare professionals should verify the current authorization and product information applicable to their country.

Storage and Handling

Pregabalin capsules should be stored according to the instructions supplied with the specific authorized medicine.

Keep medicines in their original packaging where appropriate, away from conditions that could compromise product quality, and out of reach of children.

Unused or expired medicines should be disposed of according to local pharmaceutical-waste requirements.

Important Medicine Notice

Pregabalin 75 mg is a prescription medicine and should be used only under appropriate medical supervision. This page provides general educational information and does not replace the official package leaflet, prescribing information, or advice from a qualified healthcare professional.